TITLE
Annie Li: Monitoring Sarcomas with Novel Radiation Sparing Technologies
TALK INFO
The landscape of tumor monitoring is changing, and Dr. Li’s work in sarcomas is a perfect example of this revolutionary shift. By using liquid biopsies to detect EWSR1 gene fusions in cell-free DNA, Dr. Li offers a precise, non-invasive method for tracking sarcoma progression—without the risks associated with repeated radiation exposure.
This technique allows for personalized monitoring, identifying unique fusion breakpoints in each patient and creating customized assays for real-time tumor tracking. It’s a breakthrough aligned with the principles of precision medicine, where treatment and monitoring are tailored to the individual.
Surgeons need to understand that this is more than just a technological advancement; it’s a paradigm shift in how we approach tumor management. By reducing reliance on traditional imaging, this method not only enhances monitoring accuracy but also improves long-term patient care. Dr. Li’s work is setting the stage for a new standard in cancer monitoring, and it’s one we all need to pay attention to.
THIS EVENT IS ACCREDITED
CLINICAL PATHWAY
Pathology, Medical Assessment and Management
SPEAKER
DATE
27/10/25
LEARNING OBJECTIVES
By the end of this lecture, participants will be able to:
Describe the challenges of detecting EWSR1 gene fusions in plasma cfDNA, including structural complexity and patient-specific intronic breakpoints.
Explain how liquid biopsy approaches, including cfDNA analysis, can provide a non-invasive alternative for tracking tumor burden.
Discuss the development and application of personalized assays targeting patient-specific EWSR1 fusion breakpoints.
Evaluate the potential of integrating radiation-sparing liquid biopsy strategies into longitudinal disease monitoring and clinical decision-making for sarcoma patients.
ABOUT THE SPEAKER
Annie Li, MD, Post-Doctoral Research Fellow, MGH Pathology, Harvard Medical School
CE ACCREDITATION
surgeOn is an ADA CERP Recognized Provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. surgeOn designates this activity for 1 credit hour of continuing education credits.
This event may also be accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) for a maximum of 1 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. If you are a learner based in the U.S. or Canada EACCME credits are recognized by the American Medical Association (AMA) and the Royal College of Physicians and Surgeons of Canada.
DECLARATION
In accordance with criterion 13 of document UEMS 2023.07.rev “EACCME® Criteria for the Accreditation of Live Educational Events (LEEs)” and the Standard v. Commercial or Promotional Conflict of Interest, published by the American Dental Association Continuing Education Recognition Program (ADA CERP), all surgeON presenters sign a Conflict of Interest form to document all perceived or actual conflicts of interest for the last 3 years, whether due to a financial or other relationship. This document can be viewed at the beginning of the event or on request by emailing info@surgeon-events.org No fee, honorarium or arrangement for re-imbursement of expenses in relation to the this event has been provided to the speaker.
